New Delhi. The National Institutes of Health (NIH), a part of the US Department of Health and Human Services, has uncovered the mystery of how lung cancer develops in people who have never smoked. Genomic analysis of lung cancer in people with a history of smoking has found that most of these tumors result from the accumulation of mutations caused by natural processes in the body.
The study has been conducted by an international team led by researchers from the National Cancer Institute (NCI), part of the National Institutes of Health (NIH). It describes for the first time three molecular subtypes of lung cancer in people who have never smoked.
The research findings were published earlier this week in Nature Genetics.
Maria Teresa Landi, MD, PhD, an epidemiologist in the Integrated Tumor Epidemiology Branch in the NCI’s Department of Cancer Epidemiology and Genetics, who led the research, said, “What we are seeing is that in never-smokers There are different subtypes of lung cancer, with distinct molecular features and evolutionary processes.”
The research has been carried out in collaboration with researchers from the National Institute of Environmental Health Sciences, another part of the NIH, and other institutions. “In the future we may be able to differentiate treatments based on these subtypes,” Landy said.
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